abstract：PURPOSE:To identify PAX6 mutations in patients from four Japanese families with aniridia. METHODS:Polymerase chain reaction (PCR)-single stand conformational polymorphism (SSCP) analysis (SSCA) was performed in probands of the families, and restriction analysis using MaeIII or AvaI was carried out in other affected fa...

journal_title：European journal of ophthalmology

authors： Kondo-Saitoh A,Matsumoto N,Sasaki T,Egashira M,Saitoh A,Yamada K,Niikawa N,Amemiya T

更新日期：2000-04-01 00:00:00

abstract：PURPOSE:Twenty-two people with a history of grass pollen allergic conjunctivitis were enrolled outside the pollen season in this study to compare the efficacy of 0.05% mequitazine eyedrops with topical 2% disodium cromoglycate. METHODS:This randomized, double-blind study compared right and left eyes. Subjects received...

journal_title：European journal of ophthalmology

authors： Dupin O,Trinquand C,Persi L,Bousquet J,Robert F,Arnaud B

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:To investigate color vision and its relation with the type of amblyopia and visual acuity of amblyopic eyes. METHODS:In this prospective study, 67 amblyopic eyes of 64 patients, aged from 4 to 13 years (mean 6.8 +/- 2.1) and 26 eyes of 13 control subjects aged from 5 to 13 years (mean 7.3 +/- 1.6) were examine...

journal_title：European journal of ophthalmology

authors： Koçak-Altintas AG,Satana B,Koçak I,Duman S

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:The main purpose of this prospective study was to compare the efficacy, local tolerance, and safety of topical lomefloxacin 0.3% and topical ofloxacin 0.3% in the treatment of acute bacterial conjunctivitis. PATIENTS AND METHODS:Forty patients with acute bacterial conjunctivitis were included in a randomized, ...

journal_title：European journal of ophthalmology

authors： Tabbara KF,El-Sheikh HF,Islam SM,Hammouda E

更新日期：1999-10-01 00:00:00

abstract：:Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...

journal_title：European journal of ophthalmology

authors： Bandello F,Porta M,Brancato R

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:Norrie disease (ND) is a rare X-linked recessive disorder characterized by congenital blindness, which is often associated with sensorineural hearing loss and mental retardation. X-linked familial exudative vitreoretinopathy (FEVR) is a hereditary disorder characterized by an abnormality of the peripheral retin...

journal_title：European journal of ophthalmology

authors： Shastry BS,Hiraoka M,Trese DC,Trese MT

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:To investigate a new method for assessing the thickness of the retinal nerve fiber layer thickness (NFLT) for glaucoma diagnosis, using scanning laser polarimetry. MATERIAL AND METHODS:Thirty eyes of thirty patients with ocular hypertension or glaucoma were examined using a scanning laser polarimeter. NFL T wa...

journal_title：European journal of ophthalmology

authors： Kogure S,Iijima H,Tsukahara S

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:To discover the effect of detachment of the posterior vitreous cortex on pattern electroretinogram (PERG) P50 amplitudes in the uninvolved fellow eyes (FE) of patients with macular holes (MH), and to determine the prognostic value of the PERG in identifying the FE of patients with MH that could be at risk for t...

journal_title：European journal of ophthalmology

authors： Gündüz K

更新日期：1999-01-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) undergo programmed cell death (apoptosis) after axonal injury. This cell death is mediated by several mechanisms, including deprivation of neurotrophic factors, alterations in gene expression, and production of reactive oxygen species. However, death of RGCs is delayed after axonal injury...

journal_title：European journal of ophthalmology

authors： Levin LA

更新日期：1999-01-01 00:00:00

abstract：:Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after ag...

journal_title：European journal of ophthalmology

authors： Zarbin MA

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...

journal_title：European journal of ophthalmology

authors： Esgin H,Alimgil ML,Erda S

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...

journal_title：European journal of ophthalmology

authors： Anteby I,Ramu N,Gradstein L,Miskin H,Pe'er J,Benezra D

更新日期：1998-04-01 00:00:00

abstract：AIM:A multicentre, randomized, placebo-controlled double-masked study was conducted to assess the efficacy and safety of Rimexolone 1% eye drops in reducing inflammation after cataract surgery and intra-ocular lens implantation. METHODS:Rimexolone 1% (124 patients) or placebo (58 patients) was given, four times a day ...

journal_title：European journal of ophthalmology

authors： Bron A,Denis P,Hoang-Xuan TC,Boureau-Andrieux C,Crozafon P,Hachet E,Medhorn E,Akingbehin A

更新日期：1998-01-01 00:00:00

abstract：:Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...

journal_title：European journal of ophthalmology

authors： Osuský R,Schoetzau A,Flammer J

更新日期：1997-10-01 00:00:00

abstract：:The purpose of this study was to evaluate the hemodynamic changes occurring in the ophthalmic vasculature of eyes with Behçet's disease in a controlled clinical trial. Both eyes of patients with retinal involvement due to Behçet's disease were consecutively evaluated and were established as having mild or severe retin...

journal_title：European journal of ophthalmology

authors： Uçakhan O,Salih M,Altan S,Ozdemir O

更新日期：1997-07-01 00:00:00

abstract：PURPOSE:To assess whether a screening method based on transcranial Doppler (TCD) examination could detect signs of brain hemodynamic impairment in non-insulin-dependent diabetic patients with retinal microangiopathy of varying severity, asymptomatic for cerebrovascular diseases. METHODS:We studied 86 patients stratifi...

journal_title：European journal of ophthalmology

authors： Lippera S,Gregorio F,Ceravolo MG,Lagalla G,Provinciali L

更新日期：1997-04-01 00:00:00

abstract：:To assess the utility of exfoliative cytology in the diagnosis of chronic conjunctivitis, we compared its findings with microbiological examination and established the correlation between cytology and microbiology in 32 patients with conjunctivitis lasting four weeks or more, with a nonspecific clinical picture. The m...

journal_title：European journal of ophthalmology

authors： Cvenkel B,Globocnik M

更新日期：1997-01-01 00:00:00

abstract：:The study investigated the pattern of the direct-current electroretinogram (ERG) of albino rabbits during prolonged intermittent recording, and whether different initial dark adaptation periods or starting the experiments at different times influenced the results. We examined 27 rabbits under general anesthesia, in th...

journal_title：European journal of ophthalmology

authors： Gottvall E,Textorius O

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To prospectively compare the clinical results of two cataract surgery procedures through a 4.0-mm incision, differing only in the wound location (superior or lateral). METHODS:168 eyes with cataract were randomly assigned to either procedure. Except for incision location, surgical methods were identical. Uncor...

journal_title：European journal of ophthalmology

authors： Mendívil A

更新日期：1996-10-01 00:00:00

abstract：:We report five cases with a mixture of esotropia and pseudoexotropia due to macular ectopia related cicatricial retinopathy of prematurity (ROP). On inspection, the patients, aged from 9 to 28 years, presented a divergence of the eyes and a nasally decentralised corneal light reflex. The cover test showed esodeviation...

journal_title：European journal of ophthalmology

authors： Bianchi PE,Guagliano R,Salati R,Traselli GP,Trimarchi F

更新日期：1996-10-01 00:00:00

abstract：:Astigmatic changes in three series of cataract surgical procedures were compared. The first two series comprised eyes having a manual extracapsular cataract extraction (ECCE) through a 12.0 mm or 8.0 mm incision and implant of a PMMA posterior chamber lens. The third series comprised eyes having phacoemulsification th...

journal_title：European journal of ophthalmology

authors： Cavallini GM,Lugli N,Campi L,Lazzerini A,Longanesi L

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To evaluate the long-term results of pars plana vitrectomy (PPV) and silicone oil implantation (SOI) for giant retinal tears (GT). METHODS:PPV with SOI was performed for GT in 50 eyes of 46 patients. Thirty-one eyes (62%) of 27 patients suffered from idiopathic GT. A direct injury of the eye preceded GT in 19 ...

journal_title：European journal of ophthalmology

authors： Karel I,Michalickova M,Soucek P

更新日期：1996-07-01 00:00:00

abstract：:The objectives of this study were two-fold: to identify tear histamine content and its relationship to changes in tear histaminase activity during the early (EPR) and late phases (LPR) of the allergic reaction induced by a conjunctival provocation test (CPT) and to evaluate the effects of lodoxamide on histamine relea...

journal_title：European journal of ophthalmology

authors： Leonardi AA,Smith LM,Fregona IA,Salmaso M,Secchi AG

更新日期：1996-04-01 00:00:00

abstract：PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...

journal_title：European journal of ophthalmology

authors： Atanassova-Chilova BK

更新日期：1996-04-01 00:00:00

abstract：:Vascular involvement is a well known manifestation of Behçet's disease (BD) and may effect systemic and regional circulation in patients with BD. We evaluated ophthalmic and central retinal artery flow velocities in these patients. Mean ophthalmic and central retinal artery flow velocities were lower in patients with ...

journal_title：European journal of ophthalmology

authors： Seçkin D,Baysal K,Erkan D,Oltulu Y,Akpolat T,Turanli AY

更新日期：1996-04-01 00:00:00

abstract：:Peripheral choroidal neovascularization can result in an elevated subretinal lesion which can simulate a choroidal tumor. We reviewed 8 eyes with 11 peripheral areas of subretinal fluid and exudate which were subsequently determined to be secondary to peripheral choroidal neovascularization. Previous reports of periph...

journal_title：European journal of ophthalmology

authors： Vine AK,Johnson MW

更新日期：1996-01-01 00:00:00

abstract：:Copper intraocular foreign bodies (IOFB) are relatively common after penetrating eye injuries. Ocular signs and symptoms vary greatly in relation to the copper content, ranging from chronic uveitis and severe visual loss for IOFB containing more than 85% copper, to local copper deposits with no severe ocular damage fo...

journal_title：European journal of ophthalmology

authors： Billi B,Lesnoni G,Scassa C,Giuliano MA,Coppè AM,Rossi T

更新日期：1995-10-01 00:00:00

abstract：PURPOSE:To examine the association between Lp(a) concentrations and the severity of retinopathy in 22 younger-onset and 48 older-onset diabetic subjects from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR), a population-based study of diabetic retinopathy. METHODS:We used a subset of the WESDR popula...

journal_title：European journal of ophthalmology

authors： Haffner SM,Klein BE,Moss SE,Klein R

更新日期：1995-04-01 00:00:00

abstract：:Ultrasound tissue characterization parameters of size and acoustic concentration can be used to sub-classify uveal melanoma and estimate the patient's risk of death. Histologically determined microcirculation patterns have also been found to sub-classify uveal melanoma and predict patient's risk of death. This study e...

journal_title：European journal of ophthalmology

authors： Coleman DJ,Rondeau MJ,Silverman RH,Folberg R,Rummelt V,Woods SM,Lizzi FL

更新日期：1995-04-01 00:00:00

abstract：:This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive posto...

journal_title：European journal of ophthalmology

authors： Corbett MC,Hingorani M,Boulton JE,Shilling JS

更新日期：1995-01-01 00:00:00

abstract：:Indocyanine green video-angiography (ICG) was done twice on three patients with choroidal osteoma. Choroidal osteoma consisted of two portions, a yellow-white area and a surrounding orange area. The early phase of ICG angiography showed hypofluorescence due to blockage, corresponding to the osteoma. However, the hypof...

journal_title：European journal of ophthalmology

authors： Yuzawa M,Kawamura A,Haruyama M,Matsui M

更新日期：1994-10-01 00:00:00

abstract：:The risk factors for intraoperative and early postoperative complications were evaluated in 351 consecutive cataract operations at the Oulu University Hospital in 1990. Bleeding into the anterior chamber during the operation was recorded in 8.6%, zonular rupture in 6.6%, posterior capsular rupture in 5.4% and vitreous...

journal_title：European journal of ophthalmology

authors： Lumme P,Laatikainen LT

更新日期：1994-07-01 00:00:00

abstract：:To evaluate the present level of reliability of common ultrasonography prior to vitreoretinal surgery, we carried out a prospective study to compare preoperative ultrasonography data with direct intraoperative findings. A total of 228 eyes with different vitreoretinal disorders and opaque or clear media were studied. ...

journal_title：European journal of ophthalmology

authors： Azzolini C,Pierro L,Candino M,Brancato R

更新日期：1994-04-01 00:00:00

abstract：:Idiopathic macular holes have long been considered to be a stable, untreatable condition with little or no chance of spontaneous visual improvement. Within the last few years, surgical intervention has been developed for the management of idiopathic Stage 3 and Stage 4 holes. With pars plana vitrectomy surgery, at lea...

journal_title：European journal of ophthalmology

authors： Del Priore LV

更新日期：1994-01-01 00:00:00

abstract：:In contrast to focal laser treatment of large subfoveal neovascular membranes, perifoveal laser treatment sparing the central avascular zone can partially retain central macular function in some cases. The anatomical and functional outcome of this technique was analysed in 26 patients with large subfoveal neovascular ...

journal_title：European journal of ophthalmology

authors： Schneider U,Kuck H,Kreissig I

更新日期：1993-10-01 00:00:00

abstract：:Ocular injuries are a frequent cause of monocular blindness and cause disfigurement and discomfort. We developed a measure of severity for eye injuries using a multi-attribute utility (MAU) model. The severity index scoring was applied to eye injuries that presented at hospitals in Wisconsin, U.S.A. The resulting dist...

journal_title：European journal of ophthalmology

authors： Klein BE,Karlson TA,Rose J

更新日期：1993-04-01 00:00:00

abstract：:Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...

journal_title：European journal of ophthalmology

authors： Rodriguez-Saez E,Otero-Costas J,Moreno-Montañes J,Relova JL

更新日期：1993-01-01 00:00:00

abstract：:In myopia patients, Rh and acid phosphatase were typed in two groups: group 1 consisted of 214 patients with low myopia (-6 D or less); group 2 of 124 patients with high myopia (more than -6 D). Statistical analysis of the markers showed a good Hardy-Weinberg equilibrium for both groups. In the Rh system there was a s...

journal_title：European journal of ophthalmology

authors： Olmedo MV,Muñoz JI,Rodriguez-Cid MJ,Carracedo A,Gomez-Ulla FJ,Salorio MS

更新日期：1992-10-01 00:00:00

abstract：:In renal failure the incidence of pingueculae is significantly higher than in a comparable control group but there is no evidence that the calcific precipitation in renal failure is of a dystrophic nature. The lime salts are not located within the area of elastotic degeneration, a prerequisite for dystrophic degenerat...

journal_title：European journal of ophthalmology

authors： Klaassen-Broekema N,Landesz M,Krul B,Van Bijsterveld OP

更新日期：1992-07-01 00:00:00

abstract：:The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...

journal_title：European journal of ophthalmology

authors： Murube del Castillo J,Martinez Baradas A,Hernandez King J,Cruz Vilella ME,Bahamon Caycedo M

更新日期：1992-04-01 00:00:00